Definitions of Research Activity Codes

Code Group Includes
5 Development of Treatments and Therapeutic Interventions

Discovery and development of therapeutic interventions and testing in model systems and preclinical settings

Codesort icon Includes
5.1 Pharmaceuticals

Identification and development of pharmaceutical small molecules, therapeutic vaccines, antibodies and hormones including

  • drug screening and development of delivery systems
  • mechanism of action including side effects and drug resistance
  • pharmacogenetics, prediction of genetic variation and responses to drugs
  • testing in in vitro and in vivo model systems
5.2 Cellular and gene therapies

Discovery and development of cellular, tissue and gene therapies including

  • gene therapy, stem cells therapy, in vitro fertilisation and tissue engineering
  • development of delivery systems
  • development of culture systems
  • testing in in vitro and in vivo model systems
5.3 Medical devices

Discovery and development of medical devices including

  • implantable devices, mobility aids, dressings, medical equipment and prostheses
  • biological safety assessments and investigation of adverse events
  • sterilisation and decontamination of equipment or surfaces
  • testing in in vitro and in vivo model systems
5.4 Surgery

Development of surgical, obstetric and dental interventions including

  • histocompatability, transfusions, transplantations including xenograft studies and bone marrow transplants
  • mechanisms of recovery, tolerance, rejection and side effects including infection
  • testing in in vitro and in vivo model systems
5.5 Radiotherapy

Discovery and development of interventions including

  • radiobiology, radiotherapy, radioimmunotherapy, radiosensitisers, microwaves, ultrasound, laser and phototherapy
  • development of delivery systems
  • investigation of mechanisms of action and side effects
  • testing in in vitro and in vivo model systems
5.6 Psychological and behavioural

Development of psychological and behavioural interventions including

  • cognitive behavioural therapy, electro-convulsive therapy, counselling, therapy and social interventions
  • testing in model systems
5.7 Physical

Development of physical interventions including

  • physical therapies, physiotherapy, occupational therapy, speech therapy, dietetics, exercise and osteopathy
  • mechanisms of action
  • testing in model systems
5.8 Complementary

Discovery and development of complementary approaches to conventional medical therapies including

  • hypnotherapy, meditation, massage, acupuncture and homeopathy
  • mechanisms of action
  • testing in model systems
5.9 Resources and infrastructure (development of treatments)
  • development and/or distribution of resources for general use by the research community including equipment, cell lines, tissue and DNA banks
  • infrastructure support for networks, consortia and centres